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Full Prediction Report

2026 NCAA March Madness
Complete Bracket Prediction

Generated by MiroFish Multi-Agent Simulation + Statistical Analysis • March 17, 2026

First Four (Dayton, OH)

GameWinnerReasoning
UMBC vs. HowardUMBCSlight favorite (-1.5); better overall resume
NC State vs. TexasNC StateACC experience edge; -1.5 spread
Lehigh vs. Prairie View A&MLehigh-3.5 favorite; Patriot League champion
SMU vs. Miami (OH)SMUDespite Miami OH's 31-1 record, SMU -6.5 is substantial

East Region (Washington, DC)

Round of 64

MatchupWinnerScore
(1) Duke vs. (16) SienaDuke88-54
(8) Ohio State vs. (9) TCUTCU72-68
(5) St. John's vs. (12) Northern IowaSt. John's65-58
(4) Kansas vs. (13) Cal BaptistKansas78-62
(6) Louisville vs. (11) South FloridaLouisville74-66
(3) Michigan State vs. (14) North Dakota StateMichigan State80-59
(7) UCLA vs. (10) UCFUCF UPSET71-68
(2) UConn vs. (15) FurmanUConn82-61

Round of 32

MatchupWinner
(1) Duke vs. (9) TCUDuke
(5) St. John's vs. (4) KansasSt. John's
(6) Louisville vs. (3) Michigan StateMichigan State
(10) UCF vs. (2) UConnUConn
Key: St. John's (KenPom #16, AdjD #12, Pitino coaching) edges Kansas (10 losses, Peterson hobbled).

Sweet 16

MatchupWinner
(1) Duke vs. (5) St. John'sDuke
(3) Michigan State vs. (2) UConnUConn

Elite Eight

MatchupWinner
(1) Duke vs. (2) UConnDuke
Key: Cameron Boozer (22.7 PPG, 10.2 RPG) is the best player on the floor. Duke's KenPom #1 ranking and AdjD #2 contain UConn's inconsistent offense (AdjO #30).
East Region Champion: Duke (1)

West Region (San Jose, CA)

Round of 64

MatchupWinnerScore
(1) Arizona vs. (16) LIUArizona95-52
(8) Villanova vs. (9) Utah StateUtah State68-63
(5) Wisconsin vs. (12) High PointWisconsin75-61
(4) Arkansas vs. (13) HawaiiArkansas82-64
(6) BYU vs. (11) NC StateBYU79-74
(3) Gonzaga vs. (14) Kennesaw StateGonzaga84-58
(7) Miami (FL) vs. (10) MissouriMissouri UPSET73-71
(2) Purdue vs. (15) QueensPurdue90-62

Round of 32

MatchupWinner
(1) Arizona vs. (9) Utah StateArizona
(5) Wisconsin vs. (4) ArkansasArkansas
(6) BYU vs. (3) GonzagaGonzaga
(10) Missouri vs. (2) PurduePurdue

Sweet 16

MatchupWinner
(1) Arizona vs. (4) ArkansasArizona
(3) Gonzaga vs. (2) PurduePurdue

Elite Eight

MatchupWinner
(1) Arizona vs. (2) PurdueArizona
Key: Arizona's depth (7 players averaging 8.7+ PPG) and elite defense (#3) neutralize Purdue's #2 offense. Purdue's defense (#36) is the weak link.
West Region Champion: Arizona (1)

Midwest Region (Chicago, IL)

Round of 64

MatchupWinnerScore
(1) Michigan vs. (16) UMBCMichigan82-49
(8) Georgia vs. (9) Saint LouisSaint Louis70-66
(5) Texas Tech vs. (12) AkronAkron UPSET74-71
(4) Alabama vs. (13) HofstraAlabama89-78
(6) Tennessee vs. (11) SMUTennessee66-61
(3) Virginia vs. (14) Wright StateVirginia72-53
(7) Kentucky vs. (10) Santa ClaraSanta Clara UPSET75-72
(2) Iowa State vs. (15) Tennessee StateIowa State76-51

Round of 32

MatchupWinner
(1) Michigan vs. (9) Saint LouisMichigan
(12) Akron vs. (4) AlabamaAlabama
(6) Tennessee vs. (3) VirginiaVirginia
(10) Santa Clara vs. (2) Iowa StateIowa State

Sweet 16

MatchupWinner
(1) Michigan vs. (4) AlabamaMichigan
(3) Virginia vs. (2) Iowa StateIowa State
Key: Michigan's #1 defense is the perfect antidote to Alabama's volume scoring (AdjD #67 is Alabama's fatal flaw). Iowa State's #4 defense grinds out Virginia.

Elite Eight

MatchupWinner
(1) Michigan vs. (2) Iowa StateMichigan
Midwest Region Champion: Michigan (1)

South Region (Houston, TX)

Round of 64

MatchupWinnerScore
(1) Florida vs. (16) LehighFlorida85-55
(8) Clemson vs. (9) IowaIowa71-67
(5) Vanderbilt vs. (12) McNeeseVanderbilt80-65
(4) Nebraska vs. (13) TroyNebraska64-52
(6) North Carolina vs. (11) VCUVCU UPSET68-64
(3) Illinois vs. (14) PennIllinois88-62
(7) Saint Mary's vs. (10) Texas A&MTexas A&M UPSET69-66
(2) Houston vs. (15) IdahoHouston78-48

Round of 32

MatchupWinner
(1) Florida vs. (9) IowaFlorida
(5) Vanderbilt vs. (4) NebraskaVanderbilt
(11) VCU vs. (3) IllinoisIllinois
(10) Texas A&M vs. (2) HoustonHouston

Sweet 16

MatchupWinner
(1) Florida vs. (5) VanderbiltFlorida
(3) Illinois vs. (2) HoustonHouston
Key: Houston's #5 defense contains Illinois' #1 offense in a classic style clash — defense wins in March.

Elite Eight

MatchupWinner
(1) Florida vs. (2) HoustonHouston
South Region Champion: Houston (2)

Final Four (Indianapolis, IN)

Semifinal 1: Duke (1) vs. Houston (2)

Winner: Duke. Cameron Boozer puts on a masterclass performance. Duke's #2 defense matches Houston's #5 defense, but Boozer's ability to score from all three levels is the difference-maker. Duke by 5.

Semifinal 2: Arizona (1) vs. Michigan (1)

Winner: Arizona. Arizona's seven-man scoring attack breaks through Michigan's #1 defense through sheer depth and ball movement. Michigan's tallest-in-America lineup contests everything, but Arizona's balance and Tommy Lloyd's offensive scheming find gaps. Arizona by 3 in a classic.


🏆

Arizona Wildcats

Arizona 72 — Duke 68

Arizona's unmatched roster depth overwhelms a Duke team limited by the absences of PG Caleb Foster and C Patrick Ngongba. Tommy Lloyd's squad completes a 36-2 season and brings the first national championship to Tucson since 1997.


Why Arizona Wins It All

  1. KenPom Profile: #3 overall (AdjO #5, AdjD #3) — elite two-way balance matching every historical champion benchmark
  2. Depth: Seven players averaging 8.7+ PPG is unmatched; no single-player dependency
  3. Health: Fully healthy roster — major advantage over Duke (missing PG + C)
  4. Path: West Region is considered the softest; arrives at Final Four less battle-worn
  5. Momentum: Big 12 Tournament champions; peaked at the right time
  6. Coaching: Tommy Lloyd in 5th year; deep tournament preparation experience
  7. Historical: Matches ALL six items on the champion checklist

Why Not Duke?

Despite being KenPom #1 and the tournament favorite (+300), Duke's injuries to PG Caleb Foster and C Patrick Ngongba create fatal vulnerabilities against elite competition. The simulation agents identified this as the critical factor — Duke can beat anyone with Boozer, but sustaining a 6-game run without two starters is historically unprecedented for a champion.

Upset Special: Akron over Texas Tech

The most confident upset pick. Texas Tech lost season-long star JT Toppin to an ACL tear. Akron shoots 40%+ from 3PT with Tavari Johnson at 20 PPG. The spread (TTU -7.5) underestimates the Toppin impact.